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Year : 2021  |  Volume : 7  |  Issue : 1  |  Page : 12-15

Micronutrients in hemodialysis patients: A single-center study

Department of Nephrology, Sir Ganga Ram Hospital, New Delhi, India

Correspondence Address:
Dr. Anil Kumar Bhalla
Director, Department of Nephrology, Sir Ganga Ram Hospital, New Delhi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jrnm.jrnm_13_21

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Introduction: In end-stage chronic kidney disease, nephrologists must consider the homeostasis of the multiple water-soluble ions and vitamins that are influenced by renal replacement therapy. While certain ions such as potassium and calcium are closely monitored, little is known about the handling of trace elements and vitamins in the dialysis population. Material and Methods: This was a single-centered, observational, retrospective, cross-sectional study to analyze the serum levels of clinically relevant vitamins (Vitamin D, Vitamin B12, folate) and microelements (iron, zinc) among maintenance hemodialysis (MHD) patients during June 2020–June 2021. Results: Two hundred and twenty-five patients on MHD were included in the study. The mean age was 54 years. Diabetic kidney disease (32%) was the most common basic kidney disease. The majority of patients (76%) were undergoing twice-weekly MHD. Iron was the most deficient microelement among MHD patients (64%). Vitamin D was deficient in 85% of the population. Mean zinc levels were 90 ± 18 with 19% of the patients having low zinc levels. Vitamin B12 and folate were deficient in 3% and 5% of patients, respectively. However, 40% and 32% of the patients had levels of Vitamin B12 and folate above the measurable limit. There was no association of deficient micronutrients and age, sex, and dialysis frequency. Conclusion: Iron and zinc are mostly deficient among MHD patients. Vitamin supplements should be carefully prescribed as the majority of patients had an excess of Vitamin B12 and folate rather than deficiency.

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